专利名称:Formulations of deoxycholic acid and salts
thereof
发明人:HODGE, Robert Emil,WEBSTER, Jeffrey
Douglas,MORIARTY, Robert M.
申请号:AU2018202807申请日:20180423公开号:AU2018202807B2公开日:20200116
摘要:#$%^&*AU2018202807B220200116.pdf##### ABSTRACT The present
application is directed to an aqueous pharmaceutical composition comprising from about0.4% w/v to less than about 2% w/v of a salt of deoxycholic acid, wherein the compositionis maintained at a pH from about 8.1 to about 8.5 such that the composition is stabilizedagainst precipitation. Also disclosed herein, are methods for stabilizing an aqueouspharmaceutical composition comprising from about 0.4% w/v to less than about 2% w/vof a salt of deoxycholic acid against precipitation, said method comprising maintaining pHof the solution from about 8.1 to about 8.5. 11240448_1
申请人:Kythera Biopharmaceuticals, Inc.
代理人:Spruson & Ferguson
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