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Formulations of deoxycholic acid and salts thereof

2023-10-25 来源:品趣旅游知识分享网
专利内容由知识产权出版社提供

专利名称:Formulations of deoxycholic acid and salts

thereof

发明人:HODGE, Robert Emil,WEBSTER, Jeffrey

Douglas,MORIARTY, Robert M.

申请号:AU2018202807申请日:20180423公开号:AU2018202807B2公开日:20200116

摘要:#$%^&*AU2018202807B220200116.pdf##### ABSTRACT The present

application is directed to an aqueous pharmaceutical composition comprising from about0.4% w/v to less than about 2% w/v of a salt of deoxycholic acid, wherein the compositionis maintained at a pH from about 8.1 to about 8.5 such that the composition is stabilizedagainst precipitation. Also disclosed herein, are methods for stabilizing an aqueouspharmaceutical composition comprising from about 0.4% w/v to less than about 2% w/vof a salt of deoxycholic acid against precipitation, said method comprising maintaining pHof the solution from about 8.1 to about 8.5. 11240448_1

申请人:Kythera Biopharmaceuticals, Inc.

代理人:Spruson & Ferguson

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